Pascale DELANGLE

Director

Research Activities

My research focuses among others on:
Metalloenzyme mimics to decipher the mechanism of action and design
novel therapeutic agents.
Cu(I) selective chelators, inspired from proteins involved in copper
homeostasis and targeted at the hepatocytes, to treat localized copper
accumulation in the rare Wilson’s disease.
Lanthanide and Actinide-binding peptides modeling actinide’s
interaction with proteins to understand the molecular mechanisms
responsible for their toxicity and to design peptide-based detoxification
agents.

Expertise

Research Areas

Affiliations

• CEA-Cadarache Saint-Paul lez Durance, France