My lab is focused on two fields: (1) the research of metals that bind peptides and self-assembled peptides in aim to investigate the effect of the metals on the properties of the peptide or the macromolecules that are produced from the self-assembled peptides. (2) the effect of metals on amyloid aggregation.
The lab uses innovative computational tools combined with applying extensive all-atom explicit molecular dynamics simulations. We developed an in-house force-field that precisely illustrates metal-peptide/protein interactions. Our study provides insights into the molecular mechanisms at the atomic resolution, thus allowing us to give interpretations to experimental results in addition to the prediction of results that experimentalists are not able to get in their lab.